Demi Moore has taken home the 2025 Golden Globes award for Best Actress In A Motion Picture in the Musical/Comedy category for her role in body horror film The Substance.
Moore, 62, plays Elizabeth Sparkle, an ageing Hollywood actress-turned-aerobics-workout-host who gets fired by her vulgar network boss because she is deemed ‘too old’. Somehow, Elizabeth gets involved in a body enhancement program known as The Substance, and, after many injections, goes into a state of hibernation as a younger version of herself is born in Sue (played by Margaret Qualley).
Upon accepting the golden gong, Moore recalled her early career when she, like Elizabeth, didn’t feel enough for this industry. And in her anecdote came a powerful message for all women, one which brought the room to a roaring applause.
Below, a complete transcript of Demi Moore’s Golden Globes acceptance speech:
“I’ve been doing this for over 45 years. And this is the first time I’ve ever won anything and I’m so humbled and grateful, Moore began. “Thirty years ago, I had a producer tell me that I was a popcorn actress, and at that time, I made that mean that this [award] wasn’t something that I was allowed to have.
It meant] that I could do movies that were successful and that made a lot of money but that I couldn’t be acknowledged, and I believed that. That corroded me over time, to the point where I thought a few years ago that maybe this was it, maybe I was complete, maybe I had already done what I was supposed to do.
“I was at kind of a low point and then I had this magical, bold, courageous, out-of-the-box, absolutely bonkers script come across my desk called The Substance, and the universe told me that you’re not done. I am so grateful to [director] Coralie [Fargeat] for trusting me to step in and play.
“I’ll just leave you with one thing that I think this movie is imparting:
In those moments when we don’t think we’re smart enough or pretty enough or skinny enough or successful enough, or basically just not enough—I had a woman say to me, ‘Just know, you will never be enough; but you can know the value of your worth if you just put down the measuring stick.’
“So, today I celebrate this as a marker of my wholeness and of the love that is driving me and for the gift of doing something I love and being reminded that I do belong.”
Below is the complete list of winners from the 2025 Golden Globes.
Best Picture — Drama
- A Complete Unknown
- Conclave
- Dune: Part Two
- Nickel Boys
- September 5
- The Brutalist-WINNER
Best Picture — Musical/Comedy
- A Real Pain
- Anora
- Challengers
- Emilia Pérez-WINNER
- The Substance
- Wicked
Best Actress in a Motion Picture — Drama
- Angelina Jolie, Maria
- Fernanda Torres, I’m Still Here-WINNER
- Kate Winslet, Lee
- Nicole Kidman, Babygirl
- Pamela Anderson, The Last Showgirl
- Tilda Swinton, The Room Next Door
Best Actor in a Motion Picture — Drama
- Adrien Brody, The Brutalist-WINNER
- Colman Domingo, Sing Sing
- Daniel Craig, Queer
- Ralph Fiennes, Conclave
- Sebastian Stan, The Apprentice
- Timothée Chalamet, A Complete Unknown
Best Actress in a Motion Picture — Musical/Comedy
- Amy Adams, Nightbitch
- Cynthia Erivo, Wicked
- Karla Sofía Gascón, Emilia Pérez
- Mikey Madison, Anora
- Demi Moore, The Substance-WINNER
- Zendaya, Challengers
Best Actor in a Motion Picture — Musical/Comedy
- Gabriel LaBelle, Saturday Night
- Glen Powell, Hit Man
- Hugh Grant, Heretic
- Jesse Eisenberg, A Real Pain
- Jesse Plemons, Kinds of Kindness
- Sebastian Stan, A Different Man-WINNER
Best Supporting Actress — Motion Picture
- Ariana Grande, Wicked
- Felicity Jones, Felicity Jones
- Isabella Rossellini, Conclave
- Margaret Qualley, The Substance
- Selena Gomez, Emilia Pérez
- Zoe Saldana, Emilia Pérez-WINNER
Best Supporting Actor — Motion Picture
- Denzel Washington, Gladiator II
- Edward Norton, A Complete Unknown
- Guy Pearce, The Brutalist
- Jeremy Strong, The Apprentice
- Kieran Culkin, A Real Pain-WINNER
- Yura Borizov, Anora
Best Director — Motion Picture
- Brady Corbet, The Brutalist-WINNER
- Coralie Fargeat, The Substance
- Edward Berger, Conclave
- Jacques Audiard, Emilia Pérez
- Payal Kapadia, All We Imagine as Light
- Sean Baker, Anora
Best Screenplay — Motion Picture
- Brady Corbet, Mona Fastvold, The Brutalist
- Coralie Fargeat, The Substance
- Jacques Audiard, Emilia Pérez
- Jesse Eisenberg, A Real Pain
- Peter Straughan, Conclave-WINNER
- Sean Baker, Anora
Best Picture — Animated
- Flow – WINNER
- Inside Out 2
- Memoir of a Snail
- The Wild Robot
- Wallace & Gromit: Vengeance Most Fowl
Best Picture — Non-English Language
- All We Imagine as Light
- Emilia Pérez-WINNER
- I’m Still Here
- The Girl With The Needle
- The Seed of The Sacred Fig
- Vermiglio
Best Original Song — Motion Picture
- Beautiful That Way (The Last Showgirl) — Andrew Wyatt, Miley Cyrus, Lykke Zachrisson
- Compress / Repress (Challengers) — Trent Reznor, Atticus Ross, Luca Guadagnino
- El Mal (Emilia Pérez) — Clement Ducol, Camille – WINNER
- Forbidden Road (Better Man) — Robbie Williams, Freddy Wexler, Sacha Skarbek
- Kiss The Sky (The Wild Robot) — Jordan K. Johnson, Stefan Johnson, Maren Morris, Michael Pollack, Ali Tamposi
- Mi Camino (Emilia Pérez) — Clement Ducol, Camille
Best Original Score
- Emilia Pérez
- The Brutalist
- Dune: Part Two
- The Wild Robot
- Challengers – WINNER
- Conclave
Cinematic and box office achievement
- Alien: Romulus
- Beetlejuice Beetlejuice
- Gladiator II
- Inside Out 2
- The Wild Robot
- Twisters
- Wicked – WINNER
Best Drama Series
- The Diplomat
- Mr. & Mrs. Smith
- Shōgun-WINNER
- Slow Horses
- Squid Game
- The Day of the Jackal
Best Musical/Comedy Series
- Abbott Elementary
- The Bear
- Hacks-WINNER
- Nobody Wants This
- Only Murders in the Building
- The Gentleman
Best Limited Series, Anthology Series or Television Motion Picture
- Baby Reindeer – WINNER
- Disclaimer
- Monsters: The Lyle and Erik Menendez Story
- Ripley
- The Penguin
- True Detective: Night Country
Best Actress — Drama Series
- Anna Sawai, Shōgun-WINNER
- Emma D’Arcy, House of the Dragon
- Kathy Bates, Matlock
- Keira Knightley, Black Doves
- Keri Russell, The Diplomat
- Maya Erskine, Mr. & Mrs. Smith
Best Actor — Drama Series
- Billy Bob Thornton, Landman
- Donald Glover, Mr. & Mrs. Smith
- Eddie Redmayne, The Day of the Jackal
- Gary Oldman, Slow Horses
- Hiroyuki Sanada, Shōgun-WINNER
- Jake Gyllenhaal, Presumed Innocent
Best Actor — Musical/Comedy Series
- Adam Brody, Nobody Wants This
- Jason Segel, Shrinking
- Jeremy Allen White, The Bear-WINNER
- Martin Short, Only Murders in the Building
- Steve Martin, Only Murders in the Building
- Ted Danson, A Man on the Inside
Best Actress — Comedy/Musical Series
- Ayo Edebiri, The Bear
- Jean Smart, Hacks-WINNER
- Kathryn Hahn, Agatha All Along
- Kristen Bell, Nobody Wants This
- Quinta Brunson, Abbott Elementary
- Selena Gomez, Only Murders in the Building
Best Actress — Limited Series, Anthology Series or Television Motion Picture
- Cate Blanchett, Disclaimer
- Cristin Milioti, The Penguin
- Jodie Foster, True Detective: Night Country-WINNER
- Kate Winslet, The Regime
- Naomi Watts, Feud: Capote vs. The Swans
- Sofia Vergara, Griselda
Best Actor — Limited Series, Anthology Series or Television Motion Picture
- Andrew Scott, Ripley
- Colin Farrell, The Penguin-WINNER
- Cooper Koch, Monsters: The Lyle and Erik Menendez Story
- Ewan McGregor, A Gentleman in Moscow
- Kevin Kline, Disclaimer
- Richard Gadd, Baby Reindeer
Best Supporting Actor — Television Series
- Diego Luna: La Máquina
- Ebon Moss-Bachrach: The Bear
- Harrison Ford: Shrinking
- Jack Lowden: Slow Horses
- Javier Bardem: Monsters: The Lyle and Erik Menendez Story
- Tadanobu Asano: Shōgun-WINNER
Best Supporting Actress — Television Series
- Allison Janney, The Diplomat
- Dakota Fanning, Ripley
- Hannah Einbinder, Hacks
- Jessica Gunning, Baby Reindeer-WINNER
- Kali Reis: True Detective, Night Country
- Liza Colón-Zayas, The Bear
Best Stand-Up Comedian on Television
- Adam Sandler: Love You
- Ali Wong: Single Lady-WINNER
- Jamie Foxx: What Had Happened Was
- Nikki Glaser: Someday You’ll Die
- Ramy Youssef: More Feelings
- Seth Meyers: Dad Man Walking
This story first appeared on GRAZIA International.
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